GLENDALE, Ariz. (AP) — Carson Palmer threw for 308 yards and three touchdowns and the Arizona Cardinals intercepted Jameis Winston four times in a 40-7 rout of the Tampa Bay Buccaneers on Sunday.

Marcus Cooper, acquired in a trade with Kansas City on September 2nd, had two interceptions, returning the second 60 yards for a score. Winston also fumbled the ball away once.

Winston, who had four touchdown passes against Atlanta in the opener and was NFC player of the week, threw 51 passes, the most in his two NFL seasons, completing 27 for 243 yards.

Winston had an especially rough first 30 minutes, completing 11 of 20 for 77 yards with two interceptions and a fumble. The four turnovers led to 17 Arizona points.

Injuries also hit the Buccaneers hard. First, they lost tight Luke Stocker (ankle) in the first quarter. And after a 1-yard gain on Tampa Bay’s first play of the second quarter, standout RB Doug Martin left with a hamstring injury.

Defensive end Robert Ayers Junior left with an ankle injury late in the second quarter. Finally, wide receiver Cecil Shorts III left with a hamstring injury in the third quarter.

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