(CNN) — Dickey Betts, a guitarist and the co-founder of the Allman Brothers Band, has died, according to a family statement shared with CNN on Thursday by his longtime manager.

Betts was 80.

“It is with profound sadness and heavy hearts that the Betts family announce the peaceful passing of Forrest Richard ‘Dickey’ Betts,” the statement reads. “The legendary performer, songwriter, bandleader and family patriarch passed away earlier today at his home in Osprey, FL., surrounded by his family. Dickey was larger than life, and his loss will be felt world-wide. At this difficult time, the family asks for prayers and respect for their privacy in the coming days. More information will be forthcoming at the appropriate time.”

Betts’ manager David Spero told Rolling Stone the guitarist had cancer and chronic obstructive pulmonary disease.

A native of West Palm Beach, Florida, Betts’ early musical influences included bluegrass, country music and later rock and roll. Credited with helping define the sound and of Southern rock genre of the ’60s and ‘70s, Betts, bass guitarist Berry Oakley, drummers Butch Trucks and Jaimoe joined brothers Gregg and Duane Allman to form the Allman Brothers Band in 1969. He wrote the group’s biggest hit, “Ramblin’ Man.”

Tragedy struck the group when Duane Allman died in a motorcycle accident in 1971 and Oakley was killed in a motorcycle crash a year after. Betts and Gregg Allman became the band’s leaders, but creative differences and substance abuse in the group caused them to break up and reform multiple times.

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